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Inclusion Criteria Exclusion Criteria Timeline for a Trial Participant Screening Participants are screened for eligibility to participate in the trial Treatment Participants receive retatrutide or placebo subcutaneously once weekly Follow-up Participants are monitored for safety and effectiveness after treatment What Are the Treatments Tested in This Trial

Because the drug is still being studied, researchers are continuing to monitor potential long-term risks such as cardiovascular effects and pancreatic complications

Int J Surg

These symptoms are not part of normal treatment adjustment and should never be ignored

Participation requires completion of a detailed health questionnaire